– Melatobed for insomnia: 2 mg to 3 mg of melatonin before bedtime for up to 29 weeks has been used in most research. Higher doses of up to 12 mg daily have also been used for shorter durations (up to 4 weeks).
-For reducing anxiety before surgery: 3-10 mg of melatonin taken 60-90 minutes before surgery has been used.
-For migraine: 3-4 mg of melatonin each evening for up to 6 months has been used.
-For jet lag: 0.5-8 mg of melatonin at bedtime is commonly taken on the day of arrival at the destination, continuing for 2 to 5 days. Low doses of 0.5-3 mg are often used to avoid the side effects of the higher doses.